Written by Deprecated: mb_convert_encoding(): Handling HTML entities via mbstring is deprecated; use htmlspecialchars, htmlentities, or mb_encode_numericentity/mb_decode_numericentity instead in /var/www/vhosts/definicionesyconceptos.com/httpdocs/wp-content/plugins/super-cool-ad-inserter/inc/scaip-shortcode-inserter.php on line 37
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Tabla de contenidos
El hígado es la glándula más grande del cuerpo y uno de los principales órganos del cuerpo, responsable de aprovechar las sustancias absorbidas por el intestino y de la producción de diversas proteínas. Uno de sus productos es la bilis. O cáncer de hígado puede ser de origen primario, es decir, son tumores que se originan en el órgano o pueden ser de origen metastásico, tumores que se originaron en otros órganos, se diseminan y llegan al hígado. Los tumores primarios que se originan en el hígado pueden ser de dos tipos: hepatocarcinoma o carcinoma hepatocelular, que se origina en las células básicas del hígado, llamadas hepatocitos, y colangiocarcinoma, que se origina en el epitelio de revestimiento del tracto biliar.
El carcinoma hepatocelular es el cáncer más común y agresivo y se asocia con mayor frecuencia a cirrosis, ya sea de origen viral, virus de la hepatitis B y C, alcohol o cualquier otra causa. Por otro lado, el colangiocarcinoma no tiene una causa definida específica y puede originarse dentro del hígado, en la vía biliar o fuera de la vía hepática.
Los principales factores de riesgo para el desarrollo de la enfermedad son la cirrosis y las infecciones crónicas provocadas por los virus de la hepatitis B y C.
Síntomas
Los síntomas del cáncer de hígado pueden ser silenciosos en las primeras etapas de la enfermedad, lo que dificulta el diagnóstico temprano, y cuando los síntomas se manifiestan, la enfermedad puede estar en etapas avanzadas. Los síntomas típicos incluyen dolor abdominal, masa abdominal, distensión, pérdida de peso, pérdida de apetito, malestar, ictericia (coloración amarillenta de la piel y los ojos) y ascitis (acumulación de líquido en el abdomen).
En algunos casos más graves, puede producirse la rotura espontánea del tumor, caracterizada por dolor repentino e intenso en el hipocondrio derecho, seguido de shock hipovolémico por hemorragia intraabdominal. La mayoría de los pacientes presentan niveles anormales de bilirrubina, fosfatasa alcalina y transaminasas.
Diagnóstico
El diagnóstico se puede hacer a partir de análisis de sangre, pruebas de imágenes como ultrasonido, tomografía computarizada y resonancia magnética nuclear, y extrayendo un fragmento para biopsia.
Tratamiento
El tratamiento del cáncer de hígado depende del tipo y estadio de la enfermedad. En los casos de cáncer primario, está indicada la cirugía para la extirpación completa del tumor. En los casos de carcinoma hepatocelular asociado con cirrosis, es posible que no sea posible cortar un trozo del órgano y que sea necesario un trasplante de hígado. En los casos de colangiocarcinoma, sin embargo, la indicación es la extirpación de la región afectada y si hay afuera en el canal hepático, la eliminación del canal y su reemplazo por el intestino delgado.
En los casos de metástasis hepáticas, cuando son de origen intestinal, el pronóstico suele ser mejor y el tratamiento se basa en la cirugía, mientras que en los casos de metástasis de otras regiones está indicada la quimioterapia.
Prevención
Para prevenir la enfermedad se deben tomar algunas medidas, tales como: evitar el uso frecuente y abusivo de alcohol, tomar tres dosis de la vacuna contra la hepatitis B, usar condón en todas las relaciones sexuales y no compartir el uso de agujas como forma de Evite el contacto con los virus de la hepatitis B y C. Es importante enfatizar que incluso los medicamentos comunes como ciertos analgésicos, tomados en exceso, pueden causar daños irreversibles en el hígado.
Lea también:
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